Outlook anywhere 2010 / 2013 / O365 hybrid

Hi All,

I'm hoping one of the guru's here can clear up my confusion on outlook anywhere.

We have an Exchange 2010 and 2013 environment, along with a Exchange online presence.

We recently configured Exchange 2013 outlook anywhere and noticed it overwrote client settings (Outlook 2010) on all clients with mailboxes on 2010, 2013 and Exchange online. 

From my understanding, we need to also have Outlook Anywhere configured in the exchange 2010 environment. If I set the OA configuration in 2010, will it overwrite the configuration on all clients that was set in exchange 2013?

Thanks in advance.